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师资队伍

关锦婷
职称:副教授

研究方向::生物信息、机器学习、数据挖掘

办公室

邮箱:邮箱:jtguan@xmu.edu.cn


个人简介:

2022.08至今,厦门大学,自动化系,副教授

2018.03-2022.07,厦门大学,自动化系,助理教授

2016.07-2017.01The University of Hong Kong, Centre for Genomic SciencesResearch Assistant

2014.10-2015.10Texas A&M University, Veterinary Integrative BiosciencesVisiting Scholar

2011.09-2017.09厦门大学,系统工程,工学博士

2007.09-2011.07厦门大学,自动化,工学学士


主讲课程:

模式识别与机器学习 (本科生)

生物信息学 (研究生)


承担项目:

1. 国家自然科学基金青年科学基金项目,主持。

2. 福建省自然科学基金青年项目,主持。

3. 中央高校基本科研业务费,主持。

4. 重点实验室开放课题,主持。

5. 新一代人工智能国家科技重大专项,参与。


代表性SCI期刊论文:

1. Chenqi Wang#, Yifan Lin#, Shuchao Li, Jinting Guan* (2024). Deconvolution from Bulk Gene Expression by Leveraging Sample-wise and Gene-wise Similarities and Single-cell RNA-Seq Data. BMC Genomics, 25, 875.

2. Yongjie Wang, Fengfan Zhou, Jinting Guan* (2024). SFINN: inferring gene regulatory networks from single-cell and spatial transcriptomic data with shared factor neighborhood and integrated neural networks. Bioinformatics, 40(7): btae433.

3. Yue Kang#, Hongyu Zhang#, Jinting Guan* (2024). scINRB: single-cell gene expression imputation with network regularization and bulk RNA-seq data. Briefings in Bioinformatics, 25(3): bbae148.

4. Junjie Zhang, Guoli Ji, Xilin Gao*, Jinting Guan* (2023). Single nucleus gene and gene set expression-based similarity network fusion identifies autism molecular subtypes. BMC Bioinformatics, 24, 142.

5. Jinting Guan*, Yang Wang, Yongjie Wang, Yan Zhuang, Guoli Ji (2022). SRGS: sparse partial least squares-based recursive gene selection for gene regulatory network inference, BMC Genomics 23, 782.

6. Jinting Guan*, Yan Zhuang, Yue Kang, Guoli Ji (2022). Shared and cell type-specific gene expression patterns associated with autism revealed by integrative regularized non-negative matrix factorization. Frontiers in Genetics, 13: 865371.

7. Qingyang Yin, Yang Wang, Jinting Guan*, Guoli Ji (2022). scIAE: an integrative autoencoder-based ensemble classification framework for single-cell RNA-seq data. Briefings in Bioinformatics, 23(1): bbab508.

8. Guoli Ji, Shuchao Li, Lishan Ye*, Jinting Guan* (2021). Gene module analysis reveals cell-type specificity and potential target genes in autism's pathogenesis. Biomedicines, 9(4): 410.

9. Jinting Guan*, Yiping Lin, Yang Wang, Junchao Gao, Guoli Ji (2021). An analytical method for the identification of cell type-specific disease gene modules. Journal of Translational medicine, 19: 20.

10. Jinting Guan*, Yang Wang, Yiping Lin, Qingyang Yin, Yibo Zhuang, Guoli Ji (2021). Cell type-specific predictive models perform prioritization of genes and gene sets associated with autism. Frontiers in Genetics, 11: 1778.

11. Jinting Guan*, Yiping Lin, Guoli Ji (2020). Cell Type-specific Gene Network-based Analysis Depicts the Heterogeneity of Autism Spectrum Disorder. Frontiers in Cellular Neuroscience, 14: 59.

12. Guangzao Huang, Osorio, D., Jinting Guan, Guoli Ji*, James Cai* (2020). Overdispersed gene expression characterizes schizophrenic brains. npj Schizophrenia, 6:9.

13. Jinting Guan, James Cai., Guoli Ji*, Pak Sham* (2019). Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder. Translational Psychiatry, 9 (1): 152.

14. Jinting Guan, Moliang Chen, Congting Ye, James Cai., Guoli Ji* (2018). AEGS: identifying aberrantly expressed gene sets for differential variability analysis. Bioinformatics, 34(5): 881-883.

15. Jinting Guan, Ence Yang, Jizhou Yang, Yong Zeng, Guoli Ji*, James Cai* (2016). Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis. Human Genetics, 135 (7), 797-811.

16. Brinkmeyer-Langford, C.L.#, Jinting Guan#, Guoli Ji*, James Cai* (2016). Aging shapes the population-mean and -dispersion of gene expression in human brains. Frontiers in Aging Neuroscience, 8, 1-13. (#Co-first author).

17. Guoli Ji, Jinting Guan, Yong Zeng, Qingshun Li, Xiaohui Wu* (2015). Genome-wide identification and predictive modeling of polyadenylation sites in eukaryotes. Briefings in Bioinformatics, 16 (2): 304-313.

18. Jinting Guan, Jingyi Fu, Mingcheng Wu, Liangliang Chen, Guoli Ji, Qingshun Li, Xiaohui Wu* (2015). VAAPA: a web platform for visualization and analysis of alternative polyadenylation. Computers in Biology and Medicine, 57: 20-25.

19. Xiaohui Wu*, Yong Zeng, Jinting Guan, Guoli Ji, Rongting Huang, Qingshun Li* (2015). Genome-wide characterization of intergenic polyadenylation sites redefines gene spaces in Arabidopsis thaliana. BMC Genomics, 16 (1): 511.


代表性会议论文:

1. Yusheng Jiang, Hongyu Zhang, Jinting Guan*. UFGOT: unbalanced filter graph alignment with optimal transport for cancer subtyping based on multi-omics data. The 20th International Symposium on Bioinformatics Research and Applications (ISBRA 2024).

2. Xuesheng Lin, Yusheng Jiang, Jinting Guan*. iEMNN: an iterative integration method for single-cell transcriptomic data based on network similarity enhancement and mutual nearest neighbors. 2024 International Conference on Intelligent Computing (ICIC 2024).

3. Zengzhi Yang, Yubin Wei, Xiao Yu, Jinting Guan* (2024). Dfp-Unet: A Biomedical Image Segmentation Method Based on Deformable Convolution and Feature Pyramid. The 28th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD 2024).

4. Yuanling Ma, Jinting Guan* (2022), MOCSC: a multi-omics data-based framework for cancer subtype classification. 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Las Vegas, NV, USA.